Seasonal community succession of the phyllosphere microbiome. Copeland, JK, Yuan, L, Layeghifard, M, Wang, PW, Guttman, DS. Mol Plant Microbe Interact.28,2015. PubMed PMID:25679538
Analysis of the cystic fibrosis lung microbiota via serial Illumina sequencing of bacterial 16S rRNA hypervariable regions. Maughan, H, Wang, PW, Diaz Caballero, J, Fung, P, Gong, Y, Donaldson, SL, Yuan, L, Keshavjee, S, Zhang, Y, Yau, YC, Waters, VJ, Tullis, DE, Hwang, DM, Guttman, DS. PLoS One.7,2012. PubMed PMID:23056217
Extensive remodeling of the Pseudomonas syringae pv. avellanae type III secretome associated with two independent host shifts onto hazelnut. O’Brien, HE, Thakur, S, Gong, Y, Fung, P, Zhang, J, Yuan, L, Wang, PW, Yong, C, Scortichini, M, Guttman, DS. BMC Microbiol.12,2012. PubMed PMID:22800299
B.Sc. University of Ottawa, Biopharmaceutical Science, 2009 M.Sc. University of Ottawa, Biochemistry, 2011
Publications:
Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure. Zou, A, Nadeau, K, Xiong, X, Wang, PW, Copeland, JK, Lee, JY, Pierre, JS, Ty, M, Taj, B, Brumell, JH, Guttman, DS, Sharif, S, Korver, D, Parkinson, J. Microbiome.10,2022. PubMed PMID:35965349
Accumulation of genetic variants associated with immunity in the selective breeding of broilers. Zou, A, Nadeau, K, Wang, PW, Lee, JY, Guttman, DS, Sharif, S, Korver, DR, Brumell, JH, Parkinson, J. BMC Genet.21,2020. PubMed PMID:31952471
Perturbations of the ZED1 pseudokinase activate plant immunity. Bastedo, DP, Khan, M, Martel, A, Seto, D, Kireeva, I, Zhang, J, Masud, W, Millar, D, Lee, JY, Lee, AH, Gong, Y, Santos-Severino, A, Guttman, DS, Desveaux, D. PLoS Pathog.15,2019. PubMed PMID:31269090
Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen. Lee, AH, Bastedo, DP, Youn, JY, Lo, T, Middleton, MA, Kireeva, I, Lee, JY, Sharifpoor, S, Baryshnikova, A, Zhang, J, Wang, PW, Peisajovich, SG, Constanzo, M, Andrews, BJ, Boone, CM, Desveaux, D, Guttman, DS. G3 (Bethesda).9,2019. PubMed PMID:30573466Search PubMed
Alpha Carbonic Anhydrase 5 Mediates Stimulation of ATP Synthesis by Bicarbonate in Isolated Arabidopsis Thylakoids. Fedorchuk, TP, Kireeva, IA, Opanasenko, VK, Terentyev, VV, Rudenko, NN, Borisova-Mubarakshina, MM, Ivanov, BN. Front Plant Sci.12,2021. PubMed PMID:34512677
Perturbations of the ZED1 pseudokinase activate plant immunity. Bastedo, DP, Khan, M, Martel, A, Seto, D, Kireeva, I, Zhang, J, Masud, W, Millar, D, Lee, JY, Lee, AH, Gong, Y, Santos-Severino, A, Guttman, DS, Desveaux, D. PLoS Pathog.15,2019. PubMed PMID:31269090
Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen. Lee, AH, Bastedo, DP, Youn, JY, Lo, T, Middleton, MA, Kireeva, I, Lee, JY, Sharifpoor, S, Baryshnikova, A, Zhang, J, Wang, PW, Peisajovich, SG, Constanzo, M, Andrews, BJ, Boone, CM, Desveaux, D, Guttman, DS. G3 (Bethesda).9,2019. PubMed PMID:30573466
Bacterial inactivation of the anticancer drug doxorubicin. Westman, EL, Canova, MJ, Radhi, IJ, Koteva, K, Kireeva, I, Waglechner, N, Wright, GD. Chem Biol.19,2012. PubMed PMID:23102220
Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor. Jomaa, A, Stewart, G, Mears, JA, Kireeva, I, Brown, ED, Ortega, J. RNA.17,2011. PubMed PMID:21960487
A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers. Gortzak-Uzan, L, Ignatchenko, A, Evangelou, AI, Agochiya, M, Brown, KA, St Onge, P, Kireeva, I, Schmitt-Ulms, G, Brown, TJ, Murphy, J, Rosen, B, Shaw, P, Jurisica, I, Kislinger, T. J Proteome Res.7,2008. PubMed PMID:18076136
Human serum proteins preseparated by electrophoresis or chromatography followed by tandem mass spectrometry. Marshall, J, Jankowski, A, Furesz, S, Kireeva, I, Barker, L, Dombrovsky, M, Zhu, W, Jacks, K, Ingratta, L, Bruin, J, Kristensen, E, Zhang, R, Stanton, E, Takahashi, M, Jackowski, G. J Proteome Res.3,2004. PubMed PMID:15253417
Mining biomarkers in human sera using proteomic tools. Zhang, R, Barker, L, Pinchev, D, Marshall, J, Rasamoelisolo, M, Smith, C, Kupchak, P, Kireeva, I, Ingratta, L, Jackowski, G. Proteomics.4,2004. PubMed PMID:14730686
Processing of serum proteins underlies the mass spectral fingerprinting of myocardial infarction. Marshall, J, Kupchak, P, Zhu, W, Yantha, J, Vrees, T, Furesz, S, Jacks, K, Smith, C, Kireeva, I, Zhang, R, Takahashi, M, Stanton, E, Jackowski, G. J Proteome Res.2,2003. PubMed PMID:12938926
Sequencing of argentinated peptides by means of matrix-assisted laser desorption/ionization tandem mass spectrometry. Chu, IK, Cox, DM, Guo, X, Kireeva, I, Lau, TC, McDermott, JC, Siu, KW. Anal Chem.74,2002. PubMed PMID:12033309
Julia Copeland Sequencing Technician / Bioinformatics Microbiome Specialist
Publications:
Publications:
Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal cancer. Thakur, BK, Malaise, Y, Choudhury, SR, Neustaeter, A, Turpin, W, Streutker, C, Copeland, J, Wong, EOY, Navarre, WW, Guttman, DS, Jobin, C, Croitoru, K, Martin, A. Nat Microbiol.10,2025. PubMed PMID:40033140
Characterization of liver, adipose, and fecal microbiome in obese patients with MASLD: links with disease severity and metabolic dysfunction parameters. Schwenger, KJP, Copeland, JK, Ghorbani, Y, Chen, L, Comelli, EM, Guttman, DS, Fischer, SE, Jackson, TD, Okrainec, A, Allard, JP. Microbiome.13,2025. PubMed PMID:39810228
Mother’s milk microbiota is associated with the developing gut microbial consortia in very-low-birth-weight infants. Shama, S, Asbury, MR, Kiss, A, Bando, N, Butcher, J, Comelli, EM, Copeland, JK, Greco, A, Kothari, A, Sherman, PM, Stintzi, A, Taibi, A, Tomlinson, C, Unger, S, Wang, PW, OptiMoM Feeding Group, O’Connor, DL. Cell Rep Med.5,2024. PubMed PMID:39243753
The impact of gestational diabetes on functional capacity of the infant gut microbiome is modest and transient. Chieu, RV, Hamilton, K, Ryan, PM, Copeland, J, Wang, PW, Retnakaran, R, Guttman, DS, Parkinson, J, Hamilton, JK. Gut Microbes.16,2024. PubMed PMID:38798005
Habitats Within the Plant Root Differ in Bacterial Network Topology and Taxonomic Assortativity. Fitzpatrick, CR, Copeland, J, Wang, PW, Guttman, DS, Kotanen, PM, Johnson, MTJ. Mol Plant Microbe Interact.36,2023. PubMed PMID:36463399
Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants. Asbury, MR, Shama, S, Sa, JY, Bando, N, Butcher, J, Comelli, EM, Copeland, JK, Forte, V, Kiss, A, Sherman, PM, Stintzi, A, Taibi, A, Tomlinson, C, Unger, S, Wang, PW, O’Connor, DL, OptiMoM Feeding Group. Cell Host Microbe.30,2022. PubMed PMID:35987195
Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure. Zou, A, Nadeau, K, Xiong, X, Wang, PW, Copeland, JK, Lee, JY, Pierre, JS, Ty, M, Taj, B, Brumell, JH, Guttman, DS, Sharif, S, Korver, D, Parkinson, J. Microbiome.10,2022. PubMed PMID:35965349
Invariant natural killer T cells minimally influence gut microbiota composition in mice. Lin, Q, Kuypers, M, Liu, Z, Copeland, JK, Chan, D, Robertson, SJ, Kontogiannis, J, Guttman, DS, Banks, EK, Philpott, DJ, Mallevaey, T. Gut Microbes.14,2022. PubMed PMID:35912530
Characterization and predictive functional profiles on metagenomic 16S rRNA data of liver transplant recipients: A longitudinal study. Sivaraj, S, Copeland, JK, Malik, A, Pasini, E, Angeli, M, Azhie, A, Husain, S, Kumar, D, Allard, J, Guttman, DS, Humar, A, Bhat, M. Clin Transplant.36,2022. PubMed PMID:34781411
Oligosaccharides and Microbiota in Human Milk Are Interrelated at 3 Months Postpartum in a Cohort of Women with a High Prevalence of Gestational Impaired Glucose Tolerance. LeMay-Nedjelski, L, Yonemitsu, C, Asbury, MR, Butcher, J, Ley, SH, Hanley, AJ, Kiss, A, Unger, S, Copeland, JK, Wang, PW, Stintzi, A, Bode, L, O’Connor, DL. J Nutr.151,2021. PubMed PMID:34510198
The Impact of Migration on the Gut Metagenome of South Asian Canadians. Copeland, JK, Chao, G, Vanderhout, S, Acton, E, Wang, PW, Benchimol, EI, El Sohami, A, Croitoru, K, Gommerman, JL, Guttman, DS, GEMINI Research Team. Gut Microbes.13,2021. PubMed PMID:33794735
Assessment of Inter-Laboratory Variation in the Characterization and Analysis of the Mucosal Microbiota in Crohn’s Disease and Ulcerative Colitis. Szamosi, JC, Forbes, JD, Copeland, JK, Knox, NC, Shekarriz, S, Rossi, L, Graham, M, Bonner, C, Guttman, DS, Van Domselaar, G, Surette, MG, Bernstein, CN. Front Microbiol.11,2020. PubMed PMID:32973734
Mothers of Preterm Infants Have Individualized Breast Milk Microbiota that Changes Temporally Based on Maternal Characteristics. Asbury, MR, Butcher, J, Copeland, JK, Unger, S, Bando, N, Comelli, EM, Forte, V, Kiss, A, LeMay-Nedjelski, L, Sherman, PM, Stintzi, A, Tomlinson, C, Wang, PW, O’Connor, DL. Cell Host Microbe.28,2020. PubMed PMID:32888417
Maternal Diet and Infant Feeding Practices Are Associated with Variation in the Human Milk Microbiota at 3 Months Postpartum in a Cohort of Women with High Rates of Gestational Glucose Intolerance. LeMay-Nedjelski, L, Asbury, MR, Butcher, J, Ley, SH, Hanley, AJ, Kiss, A, Unger, S, Copeland, JK, Wang, PW, Stintzi, A, O’Connor, DL. J Nutr.151,2021. PubMed PMID:32886107
Examining the relationship between maternal body size, gestational glucose tolerance status, mode of delivery and ethnicity on human milk microbiota at three months post-partum. LeMay-Nedjelski, L, Butcher, J, Ley, SH, Asbury, MR, Hanley, AJ, Kiss, A, Unger, S, Copeland, JK, Wang, PW, Zinman, B, Stintzi, A, O’Connor, DL. BMC Microbiol.20,2020. PubMed PMID:32689933
A practical assessment of nano-phosphate on soybean (Glycine max) growth and microbiome establishment. McKnight, MM, Qu, Z, Copeland, JK, Guttman, DS, Walker, VK. Sci Rep.10,2020. PubMed PMID:32499485
Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer. Irrazabal, T, Thakur, BK, Kang, M, Malaise, Y, Streutker, C, Wong, EOY, Copeland, J, Gryfe, R, Guttman, DS, Navarre, WW, Martin, A. Nat Commun.11,2020. PubMed PMID:32286276
Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Luck, H, Khan, S, Kim, JH, Copeland, JK, Revelo, XS, Tsai, S, Chakraborty, M, Cheng, K, Tao Chan, Y, Nøhr, MK, Clemente-Casares, X, Perry, MC, Ghazarian, M, Lei, H, Lin, YH, Coburn, B, Okrainec, A, Jackson, T, Poutanen, S, Gaisano, H, Allard, JP, Guttman, DS, Conner, ME, Winer, S, Winer, DA. Nat Commun.10,2019. PubMed PMID:31409776
Mycobiome Sequencing and Analysis Applied to Fungal Community Profiling of the Lower Respiratory Tract During Fungal Pathogenesis. McTaggart, LR, Copeland, JK, Surendra, A, Wang, PW, Husain, S, Coburn, B, Guttman, DS, Kus, JV. Front Microbiol.10,2019. PubMed PMID:30930884
Methods and Strategies to Examine the Human Breastmilk Microbiome. LeMay-Nedjelski, L, Copeland, J, Wang, PW, Butcher, J, Unger, S, Stintzi, A, O’Connor, DL. Methods Mol Biol.1849,2018. PubMed PMID:30298248
The evolution of separate sexes in waterhemp is associated with surprising chromosomal diversity and complexity. Kreiner, JM, Montgomery, JS, Todesco, M, Bercovich, N, Gong, Y, Elphinstone, C, Tranel, PJ, Rieseberg, LH, Wright, SI. PLoS Biol.23,2025. PubMed PMID:40587577
Pseudomonas syringae coffee blight is associated with the horizontal transfer of plasmid-encoded type III effectors. McTavish, KJ, Almeida, RND, Tersigni, J, Raimundi, MK, Gong, Y, Wang, PW, Gontijo, GF, de Souza, RM, de Resende, MLV, Desveaux, D, Guttman, DS. New Phytol.241,2024. PubMed PMID:37953378
Perturbations of the ZED1 pseudokinase activate plant immunity. Bastedo, DP, Khan, M, Martel, A, Seto, D, Kireeva, I, Zhang, J, Masud, W, Millar, D, Lee, JY, Lee, AH, Gong, Y, Santos-Severino, A, Guttman, DS, Desveaux, D. PLoS Pathog.15,2019. PubMed PMID:31269090
Arabidopsis ETHYLENE RESPONSE FACTOR 8 (ERF8) has dual functions in ABA signaling and immunity. Cao, FY, DeFalco, TA, Moeder, W, Li, B, Gong, Y, Liu, XM, Taniguchi, M, Lumba, S, Toh, S, Shan, L, Ellis, B, Desveaux, D, Yoshioka, K. BMC Plant Biol.18,2018. PubMed PMID:30261844
A Practical Guide to Quantitative Interactor Screening with Next-Generation Sequencing (QIS-Seq). Gong, Y, Desveaux, D, Guttman, DS, Lewis, JD. Methods Mol Biol.1613,2017. PubMed PMID:28849555
Expression profiles of miRNAs from bovine mammary glands in response to Streptococcus agalactiae-induced mastitis. Pu, J, Li, R, Zhang, C, Chen, D, Liao, X, Zhu, Y, Geng, X, Ji, D, Mao, Y, Gong, Y, Yang, Z. J Dairy Res.84,2017. PubMed PMID:28831974
NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Yan, D, Easwaran, V, Chau, V, Okamoto, M, Ierullo, M, Kimura, M, Endo, A, Yano, R, Pasha, A, Gong, Y, Bi, YM, Provart, N, Guttman, D, Krapp, A, Rothstein, SJ, Nambara, E. Nat Commun.7,2016. PubMed PMID:27731416
Lung microbiota across age and disease stage in cystic fibrosis. Coburn, B, Wang, PW, Diaz Caballero, J, Clark, ST, Brahma, V, Donaldson, S, Zhang, Y, Surendra, A, Gong, Y, Elizabeth Tullis, D, Yau, YC, Waters, VJ, Hwang, DM, Guttman, DS. Sci Rep.5,2015. PubMed PMID:25974282
Transcriptome microRNA profiling of bovine mammary glands infected with Staphylococcus aureus. Li, R, Zhang, CL, Liao, XX, Chen, D, Wang, WQ, Zhu, YH, Geng, XH, Ji, DJ, Mao, YJ, Gong, YC, Yang, ZP. Int J Mol Sci.16,2015. PubMed PMID:25749476
Sequence diversity and gene expression analyses of expansin-related proteins in the white-rot basidiomycete, Phanerochaete carnosa. Suzuki, H, Vuong, TV, Gong, Y, Chan, K, Ho, CY, Master, ER, Kondo, A. Fungal Genet Biol.72,2014. PubMed PMID:24880035
Metatranscriptome of an anaerobic benzene-degrading, nitrate-reducing enrichment culture reveals involvement of carboxylation in benzene ring activation. Luo, F, Gitiafroz, R, Devine, CE, Gong, Y, Hug, LA, Raskin, L, Edwards, EA. Appl Environ Microbiol.80,2014. PubMed PMID:24795366
Bioinformatic approach to identify chaperone pathway relationship from large-scale interaction networks. Gong, Y, Zhang, Z, Houry, WA. Methods Mol Biol.787,2011. PubMed PMID:21898237
Global robustness and identifiability of random, scale-free, and small-world networks. Gong, Y, Zhang, Z. Ann N Y Acad Sci.1158,2009. PubMed PMID:19348634
BSc, Biology, University of the Republic, Uruguay 2011 MSc, Ecology and Evolution, University of the Republic, Uruguay 2015 PhD, Biomedical Sciences, Autonomous University of Mexico 2019
B.Sc. Universidad de los Andes, Microbiology / Molecular Biology, 2008 Ph.D. University of Western Ontario, Biology, 2015
Email: nadia.morales@utoronto.ca
Publications:
[pmid-refs key= nmorales wrap=p]
Microbial diversity in leaves, trunk and rhizosphere of coconut palms (Cocos nucifera L.) associated with the coconut lethal yellowing phytoplasma in Grand-Lahou, Côte d’Ivoire. Morales-Lizcano NP, Hasan A, To H, Lekadou TT, Copeland J, Wang PW, Diallo HA, Konan Konan JL, Yoshioka K, Moeder W, Scott J, Arocha Rosete Y (2017). African Journal of Biotechnology. 16(27), 1534-1550. doi:10.5897/AJB2017.16006.
First report of the identification of a ‘Candidatus Phytoplasma pruni’-related strain in Trillium species in Canada. Arocha-Rosete Y, Morales-Lizcano NP, Hasan A, Yoshioka K, Moeder W, Michelutti R, Satta E, Bertaccini A, Scott J. (2016). New Disease Reports 34, 19. doi:10.5197/j.2044-0588.2016.034.019
