Lab Technician
B.Sc.F.S. Hon. Trent University, Forensic Science
Ph.D. University of Western Ontario, Biochemistry
Publications:
[pmid-refs key=aishafreeman wrap=p]

Lab Technician
B.Sc.F.S. Hon. Trent University, Forensic Science
Ph.D. University of Western Ontario, Biochemistry
Publications:
[pmid-refs key=aishafreeman wrap=p]

Calvin Mok Ph.D.
Education outreach and Bioinformatician
B. Math University of Waterloo, Faculty of Mathematics, 2005
Ph.D. University of Toronto, Institute of Medical Science, 2012
Publications:
High-throughput phenotyping of infection by diverse microsporidia species reveals a wild C. elegans strain with opposing resistance and susceptibility traits.
Mok, C, Xiao, MA, Wan, YC, Zhao, W, Ahmed, SM, Luallen, RJ, Reinke, AW.
PLoS Pathog.19,2023. PubMed PMID:36893187
An intestinally secreted host factor promotes microsporidia invasion of C. elegans.
Tamim El Jarkass, H, Mok, C, Schertzberg, MR, Fraser, AG, Troemel, ER, Reinke, AW.
Elife.11,2022. PubMed PMID:34994689
PhenoMIP: High-Throughput Phenotyping of Diverse Caenorhabditis elegans Populations via Molecular Inversion Probes.
Mok, C, Belmarez, G, Edgley, ML, Moerman, DG, Waterston, RH.
G3 (Bethesda).10,2020. PubMed PMID:32868407
Challenges and Approaches to Genotyping Repetitive DNA.
Morton, EA, Hall, AN, Kwan, E, Mok, C, Queitsch, K, Nandakumar, V, Stamatoyannopoulos, J, Brewer, BJ, Waterston, R, Queitsch, C.
G3 (Bethesda).10,2020. PubMed PMID:31757929
MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes.
Mok, CA, Au, V, Thompson, OA, Edgley, ML, Gevirtzman, L, Yochem, J, Lowry, J, Memar, N, Wallenfang, MR, Rasoloson, D, Bowerman, B, Schnabel, R, Seydoux, G, Moerman, DG, Waterston, RH.
Genetics.207,2017. PubMed PMID:28827289
Caenorhabditis elegans as a model organism for ciliopathies and related forms of photoreceptor degeneration.
Mok, CA, Héon, E.
Adv Exp Med Biol.723,2012. PubMed PMID:22183374
Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans.
Mok, CA, Healey, MP, Shekhar, T, Leroux, MR, Héon, E, Zhen, M.
PLoS Genet.7,2011. PubMed PMID:22022287
Ciliary dysfunction and obesity.
Mok, CA, Héon, E, Zhen, M.
Clin Genet.77,2010. PubMed PMID:19968672
BBS7 and TTC8 (BBS8) mutations play a minor role in the mutational load of Bardet-Biedl syndrome in a multiethnic population.
Bin, J, Madhavan, J, Ferrini, W, Mok, CA, Billingsley, G, Héon, E.
Hum Mutat.30,2009. PubMed PMID:19402160
An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.
Li, C, Inglis, PN, Leitch, CC, Efimenko, E, Zaghloul, NA, Mok, CA, Davis, EE, Bialas, NJ, Healey, MP, Héon, E, Zhen, M, Swoboda, P, Katsanis, N, Leroux, MR.
PLoS Genet.4,2008. PubMed PMID:18369462
CRYBB1 mutation associated with congenital cataract and microcornea.
Willoughby, CE, Shafiq, A, Ferrini, W, Chan, LL, Billingsley, G, Priston, M, Mok, C, Chandna, A, Kaye, S, Héon, E.
Mol Vis.11,2005. PubMed PMID:16110300

Samantha Levin
Graduate Student
Co-supervised with Dr. Darrell Desveaux
B.Sc.Hon. McMaster University, Molecular Biology and Genetics, 2021

Janis Cheng
Graduate Student
Co-supervised with Dr. Darrell Desveaux
BScH Biotechnology Queen’s University, 2021
Diploma in Advanced Biotechnology St. Lawrence College, 2021
Publications:

Racquel Singh
Graduate Student
Co-supervised with Dr. Darrell Desveaux
B.Sc. University of British Columbia 2016
B.C.S University of British Columbia 2019

Lijie Yuan
Sequencing Technician
Publications:
Seasonal community succession of the phyllosphere microbiome.
Copeland, JK, Yuan, L, Layeghifard, M, Wang, PW, Guttman, DS.
Mol Plant Microbe Interact.28,2015. PubMed PMID:25679538
Analysis of the cystic fibrosis lung microbiota via serial Illumina sequencing of bacterial 16S rRNA hypervariable regions.
Maughan, H, Wang, PW, Diaz Caballero, J, Fung, P, Gong, Y, Donaldson, SL, Yuan, L, Keshavjee, S, Zhang, Y, Yau, YC, Waters, VJ, Tullis, DE, Hwang, DM, Guttman, DS.
PLoS One.7,2012. PubMed PMID:23056217
Extensive remodeling of the Pseudomonas syringae pv. avellanae type III secretome associated with two independent host shifts onto hazelnut.
O’Brien, HE, Thakur, S, Gong, Y, Fung, P, Zhang, J, Yuan, L, Wang, PW, Yong, C, Scortichini, M, Guttman, DS.
BMC Microbiol.12,2012. PubMed PMID:22800299

Jee Lee
Sequencing Technician
B.Sc. University of Ottawa, Biopharmaceutical Science, 2009
M.Sc. University of Ottawa, Biochemistry, 2011
Publications:
Systematic profiling of the chicken gut microbiome reveals dietary supplementation with antibiotics alters expression of multiple microbial pathways with minimal impact on community structure.
Zou, A, Nadeau, K, Xiong, X, Wang, PW, Copeland, JK, Lee, JY, Pierre, JS, Ty, M, Taj, B, Brumell, JH, Guttman, DS, Sharif, S, Korver, D, Parkinson, J.
Microbiome.10,2022. PubMed PMID:35965349
Accumulation of genetic variants associated with immunity in the selective breeding of broilers.
Zou, A, Nadeau, K, Wang, PW, Lee, JY, Guttman, DS, Sharif, S, Korver, DR, Brumell, JH, Parkinson, J.
BMC Genet.21,2020. PubMed PMID:31952471
Perturbations of the ZED1 pseudokinase activate plant immunity.
Bastedo, DP, Khan, M, Martel, A, Seto, D, Kireeva, I, Zhang, J, Masud, W, Millar, D, Lee, JY, Lee, AH, Gong, Y, Santos-Severino, A, Guttman, DS, Desveaux, D.
PLoS Pathog.15,2019. PubMed PMID:31269090
Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen.
Lee, AH, Bastedo, DP, Youn, JY, Lo, T, Middleton, MA, Kireeva, I, Lee, JY, Sharifpoor, S, Baryshnikova, A, Zhang, J, Wang, PW, Peisajovich, SG, Constanzo, M, Andrews, BJ, Boone, CM, Desveaux, D, Guttman, DS.
G3 (Bethesda).9,2019. PubMed PMID:30573466Search PubMed

Inga Kireeva
Mass Spectrometry Technician
Publications:
Alpha Carbonic Anhydrase 5 Mediates Stimulation of ATP Synthesis by Bicarbonate in Isolated Arabidopsis Thylakoids.
Fedorchuk, TP, Kireeva, IA, Opanasenko, VK, Terentyev, VV, Rudenko, NN, Borisova-Mubarakshina, MM, Ivanov, BN.
Front Plant Sci.12,2021. PubMed PMID:34512677
Perturbations of the ZED1 pseudokinase activate plant immunity.
Bastedo, DP, Khan, M, Martel, A, Seto, D, Kireeva, I, Zhang, J, Masud, W, Millar, D, Lee, JY, Lee, AH, Gong, Y, Santos-Severino, A, Guttman, DS, Desveaux, D.
PLoS Pathog.15,2019. PubMed PMID:31269090
Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen.
Lee, AH, Bastedo, DP, Youn, JY, Lo, T, Middleton, MA, Kireeva, I, Lee, JY, Sharifpoor, S, Baryshnikova, A, Zhang, J, Wang, PW, Peisajovich, SG, Constanzo, M, Andrews, BJ, Boone, CM, Desveaux, D, Guttman, DS.
G3 (Bethesda).9,2019. PubMed PMID:30573466
Bacterial inactivation of the anticancer drug doxorubicin.
Westman, EL, Canova, MJ, Radhi, IJ, Koteva, K, Kireeva, I, Waglechner, N, Wright, GD.
Chem Biol.19,2012. PubMed PMID:23102220
Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor.
Jomaa, A, Stewart, G, Mears, JA, Kireeva, I, Brown, ED, Ortega, J.
RNA.17,2011. PubMed PMID:21960487
A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers.
Gortzak-Uzan, L, Ignatchenko, A, Evangelou, AI, Agochiya, M, Brown, KA, St Onge, P, Kireeva, I, Schmitt-Ulms, G, Brown, TJ, Murphy, J, Rosen, B, Shaw, P, Jurisica, I, Kislinger, T.
J Proteome Res.7,2008. PubMed PMID:18076136
Human serum proteins preseparated by electrophoresis or chromatography followed by tandem mass spectrometry.
Marshall, J, Jankowski, A, Furesz, S, Kireeva, I, Barker, L, Dombrovsky, M, Zhu, W, Jacks, K, Ingratta, L, Bruin, J, Kristensen, E, Zhang, R, Stanton, E, Takahashi, M, Jackowski, G.
J Proteome Res.3,2004. PubMed PMID:15253417
Mining biomarkers in human sera using proteomic tools.
Zhang, R, Barker, L, Pinchev, D, Marshall, J, Rasamoelisolo, M, Smith, C, Kupchak, P, Kireeva, I, Ingratta, L, Jackowski, G.
Proteomics.4,2004. PubMed PMID:14730686
Processing of serum proteins underlies the mass spectral fingerprinting of myocardial infarction.
Marshall, J, Kupchak, P, Zhu, W, Yantha, J, Vrees, T, Furesz, S, Jacks, K, Smith, C, Kireeva, I, Zhang, R, Takahashi, M, Stanton, E, Jackowski, G.
J Proteome Res.2,2003. PubMed PMID:12938926
Sequencing of argentinated peptides by means of matrix-assisted laser desorption/ionization tandem mass spectrometry.
Chu, IK, Cox, DM, Guo, X, Kireeva, I, Lau, TC, McDermott, JC, Siu, KW.
Anal Chem.74,2002. PubMed PMID:12033309