Sylva Donaldson, PhD.
Project Manager
B.Sc.Hon Queen’s University, Molecular Biology
M.Sc. University of New Brunswick, Marine Biology
Ph.D. University of Toronto, Botany
Email: sylva.donaldson@utoronto.ca
Publications:
Detection of Covid-19 Outbreaks Using Built Environment Testing for SARS-CoV-2.
Fralick, M, Nott, C, Moggridge, J, Castellani, L, Raudanskis, A, Guttman, DS, Hinz, A, Thampi, N, Wong, A, Manuel, D, McGeer, A, Doukhanine, E, Mejbel, H, Zanichelli, V, Burella, M, Donaldson, SL, Wang, PW, Kassen, R, MacFadden, DR.
NEJM Evid.2,2023. PubMed PMID:38320044
Microbiome networks and change-point analysis reveal key community changes associated with cystic fibrosis pulmonary exacerbations.
Layeghifard, M, Li, H, Wang, PW, Donaldson, SL, Coburn, B, Clark, ST, Caballero, JD, Zhang, Y, Tullis, DE, Yau, YCW, Waters, V, Hwang, DM, Guttman, DS.
NPJ Biofilms Microbiomes.5,2019. PubMed PMID:30675371
Penicillin-binding protein 3 is a common adaptive target among Pseudomonas aeruginosa isolates from adult cystic fibrosis patients treated with β-lactams.
Clark, ST, Sinha, U, Zhang, Y, Wang, PW, Donaldson, SL, Coburn, B, Waters, VJ, Yau, YCW, Tullis, DE, Guttman, DS, Hwang, DM.
Int J Antimicrob Agents.53,2019. PubMed PMID:30664925
A genome-wide association analysis reveals a potential role for recombination in the evolution of antimicrobial resistance in Burkholderia multivorans.
Diaz Caballero, J, Clark, ST, Wang, PW, Donaldson, SL, Coburn, B, Tullis, DE, Yau, YCW, Waters, VJ, Hwang, DM, Guttman, DS.
PLoS Pathog.14,2018. PubMed PMID:30532201
Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung.
Diaz Caballero, J, Clark, ST, Coburn, B, Zhang, Y, Wang, PW, Donaldson, SL, Tullis, DE, Yau, YC, Waters, VJ, Hwang, DM, Guttman, DS.
mBio.6,2015. PubMed PMID:26330513
Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis.
Clark, ST, Diaz Caballero, J, Cheang, M, Coburn, B, Wang, PW, Donaldson, SL, Zhang, Y, Liu, M, Keshavjee, S, Yau, YC, Waters, VJ, Elizabeth Tullis, D, Guttman, DS, Hwang, DM.
Sci Rep.5,2015. PubMed PMID:26047320
Lung microbiota across age and disease stage in cystic fibrosis.
Coburn, B, Wang, PW, Diaz Caballero, J, Clark, ST, Brahma, V, Donaldson, S, Zhang, Y, Surendra, A, Gong, Y, Elizabeth Tullis, D, Yau, YC, Waters, VJ, Hwang, DM, Guttman, DS.
Sci Rep.5,2015. PubMed PMID:25974282
Analysis of the cystic fibrosis lung microbiota via serial Illumina sequencing of bacterial 16S rRNA hypervariable regions.
Maughan, H, Wang, PW, Diaz Caballero, J, Fung, P, Gong, Y, Donaldson, SL, Yuan, L, Keshavjee, S, Zhang, Y, Yau, YC, Waters, VJ, Tullis, DE, Hwang, DM, Guttman, DS.
PLoS One.7,2012. PubMed PMID:23056217
The BioPAX community standard for pathway data sharing.
Demir, E, Cary, MP, Paley, S, Fukuda, K, Lemer, C, Vastrik, I, Wu, G, D'Eustachio, P, Schaefer, C, Luciano, J, Schacherer, F, Martinez-Flores, I, Hu, Z, Jimenez-Jacinto, V, Joshi-Tope, G, Kandasamy, K, Lopez-Fuentes, AC, Mi, H, Pichler, E, Rodchenkov, I, Splendiani, A, Tkachev, S, Zucker, J, Gopinath, G, Rajasimha, H, Ramakrishnan, R, Shah, I, Syed, M, Anwar, N, Babur, O, Blinov, M, Brauner, E, Corwin, D, Donaldson, S, Gibbons, F, Goldberg, R, Hornbeck, P, Luna, A, Murray-Rust, P, Neumann, E, Ruebenacker, O, Samwald, M, van Iersel, M, Wimalaratne, S, Allen, K, Braun, B, Whirl-Carrillo, M, Cheung, KH, Dahlquist, K, Finney, A, Gillespie, M, Glass, E, Gong, L, Haw, R, Honig, M, Hubaut, O, Kane, D, Krupa, S, Kutmon, M, Leonard, J, Marks, D, Merberg, D, Petri, V, Pico, A, Ravenscroft, D, Ren, L, Shah, N, Sunshine, M, Tang, R, Whaley, R, Letovksy, S, Buetow, KH, Rzhetsky, A, Schachter, V, Sobral, BS, Dogrusoz, U, McWeeney, S, Aladjem, M, Birney, E, Collado-Vides, J, Goto, S, Hucka, M, Le Novère, N, Maltsev, N, Pandey, A, Thomas, P, Wingender, E, Karp, PD, Sander, C, Bader, GD.
Nat Biotechnol.28,2010. PubMed PMID:20829833
Cytoscape Web: an interactive web-based network browser.
Lopes, CT, Franz, M, Kazi, F, Donaldson, SL, Morris, Q, Bader, GD.
Bioinformatics.26,2010. PubMed PMID:20656902
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function.
Warde-Farley, D, Donaldson, SL, Comes, O, Zuberi, K, Badrawi, R, Chao, P, Franz, M, Grouios, C, Kazi, F, Lopes, CT, Maitland, A, Mostafavi, S, Montojo, J, Shao, Q, Wright, G, Bader, GD, Morris, Q.
Nucleic Acids Res.38,2010. PubMed PMID:20576703