Sylva Donaldson

Sylva Donaldson, PhD.
Project Manager

B.Sc.Hon Queen’s University, Molecular Biology
M.Sc. University of New Brunswick, Marine Biology
Ph.D. University of Toronto, Botany

Email: sylva.donaldson@utoronto.ca




Publications:

Clark ST, Sinha U, Zhang Y, Wang PW, Donaldson SL, Coburn B, Waters VJ, Yau YCW, Tullis DE, Guttman DS, Hwang DM. Penicillin-binding protein 3 is a common adaptive target among Pseudomonas aeruginosa isolates from adult cystic fibrosis patients treated with β-lactams. Int J Antimicrob Agents. 2019 May;53(5):620-628. doi: 10.1016/j.ijantimicag.2019.01.009. Epub 2019 Jan 19. PubMed PMID: 30664925.

Layeghifard M, Li H, Wang PW, Donaldson SL, Coburn B, Clark ST, Caballero JD, Zhang Y, Tullis DE, Yau YCW, Waters V, Hwang DM, Guttman DS. Microbiome networks and change-point analysis reveal key community changes associated with cystic fibrosis pulmonary exacerbations. NPJ Biofilms Microbiomes. 2019;5:4. doi: 10.1038/s41522-018-0077-y. eCollection 2019. PubMed PMID: 30675371; PubMed Central PMCID: PMC6341074.

Diaz Caballero J, Clark ST, Wang PW, Donaldson SL, Coburn B, Tullis DE, Yau YCW, Waters VJ, Hwang DM, Guttman DS. A genome-wide association analysis reveals a potential role for recombination in the evolution of antimicrobial resistance in Burkholderia multivorans. PLoS Pathog. 2018 Dec;14(12):e1007453. doi: 10.1371/journal.ppat.1007453. eCollection 2018 Dec. PubMed PMID: 30532201; PubMed Central PMCID: PMC6300292.

Diaz Caballero J, Clark ST, Coburn B, Zhang Y, Wang PW, Donaldson SL, Tullis DE, Yau YC, Waters VJ, Hwang DM, Guttman DS. Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung. MBio. 2015 Sep 1;6(5):e00981-15. doi: 10.1128/mBio.00981-15. PubMed PMID: 26330513; PubMed Central PMCID: PMC4556809.

Clark ST, Diaz Caballero J, Cheang M, Coburn B, Wang PW, Donaldson SL, Zhang Y, Liu M, Keshavjee S, Yau YC, Waters VJ, Elizabeth Tullis D, Guttman DS, Hwang DM.Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis. Sci Rep. 2015 Jun 5;5:10932. doi: 10.1038/srep10932. PubMed PMID: 26047320; PubMed Central PMCID: PMC4456944.

Coburn B, Wang PW, Diaz Caballero J, Clark ST, Brahma V, Donaldson S, Zhang Y, Surendra A, Gong Y, Elizabeth Tullis D, Yau YC, Waters VJ, Hwang DM, Guttman DS.Lung microbiota across age and disease stage in cystic fibrosis. Sci Rep. 2015 May 14;5:10241. doi: 10.1038/srep10241. PubMed PMID: 25974282; PubMed Central PMCID: PMC4431465.

Maughan H, Wang PW, Diaz Caballero J, Fung P, Gong Y, Donaldson SL, Yuan L, Keshavjee S, Zhang Y, Yau YC, Waters VJ, Tullis DE, Hwang DM, Guttman DS. Analysis of the cystic fibrosis lung microbiota via serial Illumina sequencing of bacterial 16S rRNA hypervariable regions. PLoS One. 2012;7(10):e45791. doi: 10.1371/journal.pone.0045791. Epub 2012 Oct 2. PubMed PMID: 23056217; PubMed Central PMCID: PMC3462755.

Montojo J, Zuberi K, Rodriguez H, Kazi F, Wright G, Donaldson SL, Morris Q, Bader GD.GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop.Bioinformatics. 2010 Nov 15;26(22):2927-8. doi: 10.1093/bioinformatics/btq562. Epub 2010 Oct 5. PubMed PMID: 20926419; PubMed Central PMCID: PMC2971582.

Lopes CT, Franz M, Kazi F, Donaldson SL, Morris Q, Bader GD. Cytoscape Web: an interactive web-based network browser. Bioinformatics. 2010 Sep 15;26(18):2347-8. doi: 10.1093/bioinformatics/btq430. Epub 2010 Jul 23. PubMed PMID: 20656902; PubMed Central PMCID: PMC2935447.

Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, Franz M, Grouios C, Kazi F, Lopes CT, Maitland A, Mostafavi S, Montojo J, Shao Q, Wright G, Bader GD, Morris Q. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res. 2010 Jul;38(Web Server issue):W214-20. doi: 10.1093/nar/gkq537. PubMed PMID: 20576703; PubMed Central PMCID: PMC2896186.

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